Negamycin (hydrochloride) |
| Catalog No.GC90669 |
항생제
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Negamycin is an antibiotic originally found in Streptomyces.1 It is active against various species of bacteria, including E. coli, S. typhosa, and K. pneumoniae, when used at concentrations ranging from 3.12 to 100 µg/ml. Negamycin (250 μM) stabilizes the interaction between tRNA and ribosomes and decreases the rate of mRNA translation.2 It also restores the auditory brainstem response to sound tones in a dystrophin-deficient mdx mouse model of Duchenne muscular dystrop (DMD) when administered at a dose of 100 mg/kg.3
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