NFF-3 (trifluoroacetate salt) |
| Catalog No.GC91852 |
NFF-3 is a fluorogenic substrate of matrix metalloproteinases (MMPs).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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NFF-3 is a fluorogenic substrate of matrix metalloproteinases (MMPs).[1] NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1*M-1) and slowly by MMP-9 (kcat/Km = 10,100 s-1*M-1) with no significant hydrolysis by MMP-1 or MMP-2.[1] NFF-3 can be used to differentiate MMP-3 activity from that of other MMPs.1,2
References:
[1].Giricz, O., Lauer, J.L., and Fields, G.B.Comparison of Metalloproteinase protein and activity profilingAnal. Biochem.409(1)37-45(2011).
[2].Nagase, H., Fields, C.G., and Fields, G.B.Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3)J. Biol. Chem.269(33)20952-20957(1994).
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