NG 012 (Synonyms: BK223-A) |
Catalog No.GC44389 |
신경 성장 인자(NGF)의 강화제인 NG 012는 Penicillium verruculosum F-4542의 배양액에서 분리되었다. NG 012는 쥐 갈색세포종 세포주(PC12)에서 NGF에 의해 유도된 신경돌기 성장을 강화합니다.
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Cas No.: 141731-76-2
Sample solution is provided at 25 µL, 10mM.
NG 012 is a fungal metabolite originally isolated from P. verruculosum that has fungicidal and nerve growth factor-potentiating properties. It inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro. NG 012 (50 μM) increases the efficacy of the antifungal miconazole against C. albicans, reducing the IC50 value from 19.2 to 2.5 μM. It also potentiates neurite outgrowth induced by nerve growth factor (NGF) in PC12 cells in a concentration-dependent manner.
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