Nimesulide D5 (Synonyms: R805-d5) |
| Catalog No.GC39583 |
Nimesulide D5는 Nimesulide로 표시된 중수소입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1330180-22-7
Sample solution is provided at 25 µL, 10mM.
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Nimesulide D5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties[1][2].
[1]. Vago T, et al. Effect of nimesulide action time dependence on selectivity towards prostaglandin G/H synthase/cyclooxygenase activity. Arzneimittelforschung. 1995 Oct;45(10):1096-8. [2]. Werner MF, et al. Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms. Eur J Pharmacol. 2006 Aug 14;543(1-3):181-9.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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