>>Signaling Pathways>> Proteases>> Drug Metabolite>>Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1)

Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1)

Catalog No.GC33452

니라파립 대사산물 M1(니라파립 카르복실산 대사산물 M1)은 니라파립의 대사산물이며, 후자는 새로운 폴리(ADP-리보스) 중합효소(PARP) 억제제로 작용합니다.

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Niraparib metabolite M1 (Niraparib carboxylic acid metabolite M1) Chemical Structure

Cas No.: 1476777-06-6

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$357.00
재고 있음
1mg
US$138.00
재고 있음
5mg
US$506.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.

Niraparib metabolite M1 has the validation in plasma and urine for the support of clinical studies such as the mass balance study and the absolute bioavailability study[1].

[1]. van Andel L, et al. Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 19;1040:14-21.

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