NL-1 |
| Catalog No.GC39411 |
NL-1은 항백혈병 효과가 있는 mitoNEET 억제제입니다. NL-1은 각각 47.35μM 및 56.26μM의 IC50으로 REH 및 REH/Ara-C 세포 성장을 억제합니다. 백혈병 세포에서 NL-1 매개 사멸은 자가포식 경로의 활성화를 필요로 합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 188532-26-5
Sample solution is provided at 25 µL, 10mM.
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NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 µM and 56.26 µM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway[1].
[1]. Geldenhuys WJ, et al. The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia. J Pharmacol Exp Ther. 2019 Jul;370(1):25-34.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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