NMDAR-TRPM4 blocker C19 dihydrochloride - FMP-A-02 | Aliudanexin |
| Catalog No.GB40296 |
C19 is an NMDAR/TRPM4 (N/T) interaction interface inhibitor with an IC50 value of 1.1 μM for NMDA-induced cell death in hippocampal neurons. This inhibitor strongly reduced NMDA-triggered toxicity and mitochondrial dysfunction, abolished cyclic adenosine monophosphate-responsive element-binding protein (CREB) shutoff, boosted gene induction, and reduced neuronal loss in mouse models of stroke and retinal degeneration. Potent neuroprotectant.NMDAR-TRPM4 blocker C8 is available as NMDAR-TRPM4 blocker C8 dihydrochloride.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2241128-93-6
Sample solution is provided at 25 µL, 10mM.
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C19 is an NMDAR/TRPM4 (N/T) interaction interface inhibitor with an IC50 value of 1.1 μM for NMDA-induced cell death in hippocampal neurons. This inhibitor strongly reduced NMDA-triggered toxicity and mitochondrial dysfunction, abolished cyclic adenosine monophosphate-responsive element-binding protein (CREB) shutoff, boosted gene induction, and reduced neuronal loss in mouse models of stroke and retinal degeneration. Potent neuroprotectant.NMDAR-TRPM4 blocker C8 is available as NMDAR-TRPM4 blocker C8 dihydrochloride.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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