NPS ALX Compound 4a dihydrochloride |
Catalog No.GC12744 |
NPS ALX 화합물 4a 이염산염은 IC50이 7.2nM이고 Ki가 0.2nM인 강력하고 선택적인 5-히드록시트립타민6(5-HT6) 수용체 길항제입니다.
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Cas No.: 299433-10-6
Sample solution is provided at 25 µL, 10mM.
NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM[1].
References:
[1]. Isaac M, et al. 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindolesderivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21.
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