NR 7h |
| Catalog No.GC50740 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2550399-06-7
Sample solution is provided at 25 µL, 10mM.
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Potent and selective p38α and p38β degrader (DC50 < 50 nM). Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM). Exhibits similar effect to p38α gene knockout in BBL358 cells. Active in vivo.
Review for NR 7h
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
Review for NR 7h
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