Nudifloramide-d3 |
Catalog No.GC66377 |
Nudifloramide-d3(2PY-d3)는 Nudifloramide로 표시된 중수소입니다. 821d96072c2d58d8970e76f526b0f6b8Nudifloramide(2PY)는 nicotinamide-adenine dinucleotide(NAD) 분해의 최종 생성물 중 하나입니다. 821d96072c2d58d8970e76f526b0f6b8Nudifloramide는 in vitro에서 poly(ADP-ribose) polymerase(PARP-1) 활성을 상당히 억제합니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 1207384-48-2
Sample solution is provided at 25 µL, 10mM.
Nudifloramide-d3 (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
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