NVP-2 |
Catalog No.GC34056 |
NVP-2는 강력하고 선택적인 ATP-경쟁적 사이클린 의존성 키나제 9(CDK9) 프로브이며 0.514nM의 IC50으로 CDK9/CycT 활성을 억제합니다. NVP-2는 각각 0.584μM, 0.706μM 및 0.605μM의 IC50 값으로 CDK1/CycB, CDK2/CycA 및 CDK16/CycY 키나제에 대한 억제 효과를 표시합니다. NVP-2는 세포 사멸을 유도합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1263373-43-8
Sample solution is provided at 25 µL, 10mM.
NVP-2 is a CDK9 inhibitor with an IC50 of 0.5 nM.
[1]. Wang J, et al. SnapShot: Kinase Inhibitors I. Mol Cell. 2015 May 21;58(4):708.e1.
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