>>Signaling Pathways>> DNA Damage/DNA Repair>> CDK>>NVP-2

NVP-2

Catalog No.GC34056

NVP-2는 강력하고 선택적인 ATP-경쟁적 사이클린 의존성 키나제 9(CDK9) 프로브이며 0.514nM의 IC50으로 CDK9/CycT 활성을 억제합니다. NVP-2는 각각 0.584μM, 0.706μM 및 0.605μM의 IC50 값으로 CDK1/CycB, CDK2/CycA 및 CDK16/CycY 키나제에 대한 억제 효과를 표시합니다. NVP-2는 세포 사멸을 유도합니다.

Products are for research use only. Not for human use. We do not sell to patients.

NVP-2 Chemical Structure

Cas No.: 1263373-43-8

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$152.00
재고 있음
1mg
US$58.00
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5mg
US$135.00
재고 있음
10mg
US$234.00
재고 있음
50mg
US$864.00
재고 있음
100mg
US$1,485.00
재고 있음

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고객 리뷰

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

NVP-2 is a CDK9 inhibitor with an IC50 of 0.5 nM.

[1]. Wang J, et al. SnapShot: Kinase Inhibitors I. Mol Cell. 2015 May 21;58(4):708.e1.

리뷰

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