O-Desmethyl Midostaurin-d5 (Synonyms: CGP62221-d5; O-Desmethyl PKC412-d5) |
| Catalog No.GC61148 |
O-Desmethyl PKC412-d5(CGP62221-d5)는 O-Desmethyl PKC412로 표시된 중수소입니다. O-데스메틸 미도스타우린(CGP62221; O-데스메틸 PKC412)은 시토크롬 P450 간 효소 대사를 통한 미도스타우린의 활성 대사 산물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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O-Desmethyl PKC412-d5 (CGP62221-d5) is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism[1].
[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83.
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