ODM-203 |
| Catalog No.GC64950 |
ODM-203은 FGFR3/1/2 및 VEGFR3/2/1/4에 대해 IC50 값이 각각 6, 11, 16, 5, 9, 26 및 35nM인 경구 활성 및 선택적 FGFR/VEGFR 억제제입니다. ODM-203은 강력한 항종양 활성을 가지며 종양 미세 환경에서 면역 반응을 활성화합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1430723-35-5
Sample solution is provided at 25 µL, 10mM.
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ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity[1].
[1]. HolmstrÖm TH, et al. ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Mol Cancer Ther. 2019 Jan;18(1):28-38.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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