ONO-9780307 |
| Catalog No.GC63128 |
ONO-9780307은 IC50 값이 2.7nM인 특정 합성 LPA1(리소포스파티딘산 수용체 1) 길항제입니다.
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Cas No.: 856691-44-6
Sample solution is provided at 25 µL, 10mM.
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ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1].
VT107 (0.1~10000 μM; LPA1-B103 and Vector-B103 cells) results in inhibition of Ca2+ mobilization[1].ONO-9780307 is used to solve the LPA1 crystal structure, binds to an orthosteric site in LPA1[1].
[1]. Mizuno H, et al. Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry. J Lipid Res. 2019;60(1):212-217.
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