Palmatine |
| Catalog No.GC39127 |
팔마틴은 HEK 293-hIDO-1 및 rhIDO-1에 대해 각각 3μM 및 157μM의 IC50을 갖는 경구 활성 및 비가역적 인돌아민 2,3-디옥시게나제 1(IDO-1) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3486-67-7
Sample solution is provided at 25 µL, 10mM.
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Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. Palmatine can ameliorate DSS-induced colitis by mitigating colonic injury, preventing gut microbiota dysbiosis, and regulating tryptophan catabolism. Palmatine has the potential for colitis treatment[1].
[1]. Zhang XJ, et al. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.Pharmacol Res. 2018 Nov;137:34-46.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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