Pelitrexol (AG 2037) |
| Catalog No.GC33188 |
Pelitrexol(AG 2037)(AG 2037)은 퓨린 생합성 효소인 글리신아미드 리보뉴클레오티드 포르밀트랜스퍼라제(GARFT)의 억제제입니다. Pelitrexol(AG 2037)은 또한 mTORC1 의무 활성화제인 GTP 결합 Rheb 수준을 감소시켜 mTORC1을 억제합니다. Pelitrexol(AG 2037)은 마우스에서 강력한 종양 성장 억제를 보여줍니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 446022-33-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT).
[1]. Emmanuel N, et al. Purine Nucleotide Availability Regulates mTORC1 Activity through the Rheb GTPase. Cell Rep. 2017 Jun 27;19(13):2665-2680.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *