Pentanoyl-Coenzyme A (sodium salt) (Synonyms: C5-CoA,Pentanoyl-CoA,Valeryl-CoA,Valeryl-Coenzyme A) |
| Catalog No.GC91818 |
Pentanoyl-coenzyme A (pentanoyl-CoA) is a derivative of CoA that contains the short-chain saturated fatty acid pentanoic acid and a metabolite of 3-oxovalproyl-CoA.
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Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Pentanoyl-coenzyme A (pentanoyl-CoA) is a derivative of CoA that contains the short-chain saturated fatty acid pentanoic acid and a metabolite of 3-oxovalproyl-CoA.[1] It is formed from 3-oxovalproyl-CoA by mitochondrial thiolases. Hepatic levels of pentanoyl-CoA and propionyl-CoA are increased in an Apc+/Min-FCCC mouse model of spontaneous colorectal cancer fed a low- or high-fat diet.[2]
References:
[1].Silva, M.F., Ruiter, J.P., Overmars, H., et al.Complete β-oxidation of valproate: Cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolaseBiochem. J.362(Pt 3)755-760(2002).
[2].Dazard, J.-E., Sandlers, Y., Doerner, S.K., et al.Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancerBMC Syst. Biol.8:72(2014).
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