Pifusertib hydrochloride (Synonyms: TAS-117 hydrochloride) |
Catalog No.GC69991 |
Pifusertib (TAS-117) hydrochloride는 유효하고 선택적이며 경구용 활성을 가진 Akt 억제제의 이성질체입니다(Akt1, 2 및 3에 대한 IC50 각각 4.8, 1.6 및 44 nM). Pifusertib hydrochloride는 골수종 항암 활성을 자극하고 프로테아소마 저해제 유도의 치명적인 엔도플라즈므르 스트레스를 증가시킵니다. Pifusertib hydrochloride는 세포 사멸(apoptosis)과 자가식(autophagy)을 유도합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2930090-28-9
Sample solution is provided at 25 µL, 10mM.
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