(-)-Pinoresinol |
| Catalog No.GC90533 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 81446-29-9
Sample solution is provided at 25 µL, 10mM.
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(−)-Pinoresinol is a lignan that has been found in Manihot esculenta and has diverse biological activities.1,2,3 It scavenges DPPH and ABTS radicals in cell-free assays (EC50s = 0.2 and 0.055 mg/ml, respectively).1 (−)-Pinoresinol selectively inhibits 5-lipoxygenase (5-LO) and 15-LO over COX-2 (IC50s = 13.8, 3.5, and >100 µM, respectively).2 It also inhibits LPS-induced nitric oxide (NO) production in BV-2 microglial cells (IC50 = 34.25 µM).3
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