Poly-L-lysine hydrochloride |
| Catalog No.GC63849 |
Poly-L-lysine hydrochloride는 세포막의 음으로 하전된 이온과 배양 표면 사이의 정전기적 상호작용을 향상시켜 고체 기질에 대한 세포 부착을 촉진하는 데 유용한 세포의 비특이적 부착 인자입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 26124-78-7
Sample solution is provided at 25 µL, 10mM.
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Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide.[1].
Poly-L-lysine is a food-grade antimicrobial peptide that forms complexes with proteins. Such complexes are potential carriers for targeted delivery of agents. Electrostatic potential modelling of EPL was employed to describe the interaction affinity. A three-dimensional phase boundary curve was established which divided the complexation into a nano-scale and phase separation[2].
[1]. Archishman Ghosh, et al. Three archetypical classes of macromolecular regulators of protein liquid-liquid phase separation. Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19474-19483.
[2]. Liang Guo, et al. pH-induced structural transition during complexation and precipitation of sodium caseinate and ε-Poly-l-lysine. Int J Biol Macromol. 2020 Jul 1;154:644-653.
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