Pom-8PEG |
| Catalog No.GC63149 |
E3 리가아제 리간드-링커 접합체인 Pom-8PEG는 E3 유비퀴틴 리가아제에 대한 세레블론(CRBN) 리간드와 8-단위 PEG 링커를 통합합니다. Pom-8PEG는 IDO1 PROTAC 분해제와 같은 PROTAC의 합성에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2488761-03-9
Sample solution is provided at 25 µL, 10mM.
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Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader[1].
[1]. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953.
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
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