Pomalidomide-PEG3-C2-NH2 TFA |
| Catalog No.GC61201 |
Pomalidomide-PEG3-C2-NH2 TFA는 합성된 E3 리가제 리간드-링커 접합체로, PROTAC 기술에 사용되는 Pomalidomide 기반 세레블론 리간드 및 3-단위 PEG 링커를 통합합니다.
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Cas No.: 2414913-97-4
Sample solution is provided at 25 µL, 10mM.
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Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
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