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Propyphenazone-d3

Catalog No.GC71602

Propyphenazone-d3는 프로필페나존으로 표기된 중수소이다.

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Propyphenazone-d3 Chemical Structure

Cas No.: 162935-29-7

Size 가격 재고 수량
1 mg
US$153.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Propyphenazone-d3 is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Burdan F, et al. Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration. Cells Tissues Organs. 2002;171(2-3):145-51.

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