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PROTAC IRAK4 degrader-1

Catalog No.GC62197

PROTAC IRAK4 분해자-1은 특허 US20190192668A1 화합물 I-210에서 추출한 Cereblon 기반 PROTAC 인터루킨-1 수용체 관련 키나제 4(IRAK4) 분해자로 0.01 및 0.1에서 20-50% 및 >50% IRAK4 분해를 만듭니다. OCI-LY-10 세포에서 각각 1μM.

Products are for research use only. Not for human use. We do not sell to patients.

PROTAC IRAK4 degrader-1 Chemical Structure

Cas No.: 2360533-90-8

Size 가격 재고 수량
5 mg
US$1,125.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

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