(R)-IDO/TDO-IN-1 |
| Catalog No.GC70609 |
(R)-IDO/TDO-IN-1 화합물 25는 indoleamine-2,3-dioxygenase IDO 억제제로 약리성이 좋다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2033173-00-9
Sample solution is provided at 25 µL, 10mM.
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(R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor, with good pharmacokinetic properties. (R)-IDO/TDO-IN-1 exhibits anti-tumor activity in MC38 xenograft model. (R)-IDO/TDO-IN-1 shows synergistic effect with anti-PD-1 monoclonal antibody (SHR-1210).
References:
[1]. Tu W, Yang F, Xu G, Chi J, Liu Z, Peng W, Hu B, Zhang L, Wan H, Yu N, Jin F, Hu Q, Zhang L, He F, Tao W. Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors. ACS Med Chem Lett. 2019 Jun 3;10(6):949-953.
Review for (R)-IDO/TDO-IN-1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for (R)-IDO/TDO-IN-1
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