>>(R)-TTBK1-IN-1

(R)-TTBK1-IN-1

Catalog No.GC70719

(R)-TTBK1-IN-1 는 강력하고 선택적이며 뇌 침투성의 tau 마이크로 튜브 단백질 효소 1 TTBK1 억제제입니다.

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(R)-TTBK1-IN-1 Chemical Structure

Cas No.: 2735015-59-3

Size 가격 재고 수량
1 mg
US$160.00
재고 있음
5 mg
US$351.00
재고 있음
10 mg
US$558.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
(R)-TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor. (R)-TTBK1-IN-1 is an enantiomer of TTBK1-IN-1 . (R)-TTBK1-IN-1 can be used in the research of alzheimer’s disease and related tauopathies. (R)-TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References:
[1]. Halkina T, et, al. Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo. J Med Chem. 2021 May 13;64(9):6358-6380.

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