(Rac)-AMG8379 |
| Catalog No.GC70292 |
(Rac)-AMG8379 Rac-AMG8380은 AMG8379의 레이스 메이트입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1641574-26-6
Sample solution is provided at 25 µL, 10mM.
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(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide antagonist of NaV1.7, with IC50s of 8.5 and 18.6 nM for hNaV1.7 and mNaV1.7, respectively .
References:
[1]. Kornecook TJ, et al. Pharmacologic Characterization of AMG8379, a Potent and Selective Small Molecule Sulfonamide Antagonist of the Voltage-Gated Sodium Channel NaV1.7. J Pharmacol Exp Ther. 2017 Jul;362(1):146-160.
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