Regorafénib N-oxyde M2 |
Catalog No.GC33333 |
레고라페닙 N-옥시드 M2는 레고라페닙의 활성 대사산물입니다. 레고라페닙은 IC50이 각각 13/4.2/46, 22, 7, 1.5 및 2.5nM인 VEGFR1/2/3, PDGFRβ, Kit, RET 및 Raf-1에 대한 다중 표적 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 835621-11-9
Sample solution is provided at 25 µL, 10mM.
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
[1]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48.
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(Based on Reviews and 29 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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