1-β-D-Glucosylsphingadienine (d18:2 (4E,8E)) (Synonyms: Glucosylsphingadienine (d18:2 (4E,8E)), 1-β-D-Glucosylsphingadienine (plant), Glucosylsphingosine (plant)) |
| Catalog No.GC42050 |
1-β-D-글루코실스핑가디에닌(d18:2(4E,8E))은 글루코실세레브로사이드의 탈아세틸화된 리소지질 유도체인 글루코실스핑고신입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 114200-59-8
Sample solution is provided at 25 µL, 10mM.
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1-β-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 μM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gaucher's disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3); thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-β-D-glucosylsphingadienine isolated from plants.
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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