(±)12-HETE (Synonyms: (±)-Hydroxyeicosatetraenoic Acid) |
Catalog No.GC40429 |
(±)12-LOX 촉매를 사용하는 아라키돈산의 주요 대사 산물인 12-HETE는 용량 의존적 방식으로 세포 사멸을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71030-37-0
Sample solution is provided at 25 µL, 10mM.
(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers . It aggregates neutrophils with an EC50 value of 40 nM.[1]
Reference:
[1]. O'Flaherty, J.T., Thomas, M.J., Lees, C.J., et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. American Journal of Pathology 104, 55-62 (1981).
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