>>Signaling Pathways>> PROTAC>>Amine-PEG-thiol (MW 3400)

Amine-PEG-thiol (MW 3400)

Catalog No.GC60577

아민-PEG-티올(MW 3400)은 PROTAC 합성에 사용할 수 있는 PEG 기반 PROTAC 링커입니다.

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Amine-PEG-thiol (MW 3400) Chemical Structure

Size 가격 재고
100mg
US$426.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Amine-PEG-thiol (MW 3400) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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