Davunetide |
Catalog No.GC50733 |
Davunetide는 포유류 CNS에 존재하는 신경영양 인자인 활성 의존성 신경보호 단백질(ADNP)에서 파생된 8개의 아미노산 조각입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 211439-12-2
Sample solution is provided at 25 µL, 10mM.
Highly potent active component of activity-dependent neuroprotective protein (ADNP). Prevents β-amyloid aggregation. Reduces hyperphosphorylated tau levels and increases tau-microtubule interactions; neuroprotective at femtomolar concentrations in vitro. Exerts neuroprotective effects in schizophrenia models associated with microtubule-autophagy insufficiency in MAP6-deficient mice. Modulates HIFs and VEGF expression and suppresses retinal cell apoptosis in an in vivo diabetic retinopathy model.
Average Rating: 5
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