Afzelin (Synonyms: Kaempferin, Kaempferol 3-O-rhamnoside, Kaempferol 3-O-α-L-rhamnopyranoside) |
| Catalog No.GC35262 |
Afzelin(Kaempferol-3-O-rhamnoside)은 Houttuynia cordata Thunberg에서 발견되는 플라보놀 배당체이며 항균 및 해열제, 해독제 제조 및 염증 치료에 널리 사용됩니다.
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Cas No.: 482-39-3
Sample solution is provided at 25 µL, 10mM.
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Afzelin (Kaempferol-3-O-rhamnoside) is is a flavonol glycoside found in Houttuynia cordata Thunberg and is widely used in the preparation of antibacterial and antipyretic agents, detoxicants and for the treatment of inflammation. Afzelin attenuates the mitochondrial damage, enhances mitochondrial biogenesis and decreases the level of mitophagy-related proteins, parkin and PTEN-induced putative kinase 1. Afzelin improves the survival rate and reduces the serum levels of alanine aminotransferase and pro-inflammatory cytokines in D-galactosamine (GalN)/LPS -treated mice[1].
[1]. Lee SB, et al. Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics. Br J Pharmacol. 2017 Jan;174(2):195-209.
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