BuChE-IN-TM-10 (Synonyms: TM-10) |
Catalog No.GC35564 |
BuChE-IN-TM-10(TM-10)은 IC50이 8.9nM인 강력한 부티릴콜린에스테라제(BuChE) 억제제입니다.
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Cas No.: 2313524-95-5
Sample solution is provided at 25 µL, 10mM.
BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer's disease[1]. IC50: 8.9 nM (BuChE)[1].
[1]. Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.
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