Mal-PEG2-VCP-Eribulin |
| Catalog No.GC36533 |
Mal-PEG2-VCP-Eribulin은 ADC 링커(Mal-PEG2-VCP)와 Eribulin으로 구성됩니다. 에리불린은 암에 대한 기계적으로 독특한 미세소관 억제제입니다. Mal-PEG2-VCP-Eribulin은 항체 접합체를 위한 Eribulin 기반 약물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2130869-18-8
Sample solution is provided at 25 µL, 10mM.
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Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. Mal-PEG2-VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].
[1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. [2]. Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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