NP-12 (TFA) |
| Catalog No.GC36768 |
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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NP-12 (TFA) is a peptide antagonist of the PD-1 signaling pathway, displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. NP-12 (TFA) exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs)[1]. PD-1 signaling pathway[1]
[1]. Sasikumar PG, et al. A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy. Mol Cancer Ther. 2019 Jun;18(6):1081-1091.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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