GPR30 agonist-1 |
| Catalog No.GC61817 |
GPR30 작용제-1은 G 단백질 결합 수용체 30(GPR30) 작용제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 415919-74-3
Sample solution is provided at 25 µL, 10mM.
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GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects[1].
GPR30 agonist-1 (compound 5408-0877) (1 nM-10 µM) induces a concentration-dependent relaxation in carotid arteries from both male and female rats. GPR30 agonist-1-induced relaxation is abolished by endothelium removal and abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 µM)[1].
References:
[1]. Brad R S Broughton, et al. Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1055-61.
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