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홈 >> Signaling Pathways >> Membrane Transporter/Ion Channel >> GTPase

GTPase

Products for  GTPase

  1. Cat.No. 상품명 정보
  2. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  3. GC42579 6H05 (trifluoroacetate salt) The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. 6H05 (trifluoroacetate salt) Chemical Structure
  4. GC11483 8-CPT-2Me-cAMP, sodium salt

    8-CPT-2MecAMP, 8-pCPTcAMP, 8-pCPT-2′-OMe-cAMP

     8-CPT-2Me-cAMP, 나트륨 염은 작은 GTPase Rap1 및 Rap2에 대한 cAMP 민감성 구아닌 뉴클레오티드 교환 인자(GEF)인 cAMP(Epac)에 의해 활성화된 교환 단백질의 선택적 활성제입니다. 8-CPT-2Me-cAMP, sodium salt Chemical Structure
  5. GC18426 8-Nitroguanine 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. 8-Nitroguanine Chemical Structure
  6. GC16199 8-pCPT-2-O-Me-cAMP-AM Epac activator 8-pCPT-2-O-Me-cAMP-AM Chemical Structure
  7. GC39810 CID44216842

    Cdc42-IN-1

     CID44216842(Cdc42-IN-1)는 강력한 Cdc42 선택적 구아닌 뉴클레오티드 결합 납 억제제입니다. Cdc42 WT 및 Cdc42Q61L 돌연변이에 대한 EC50은 GTP 결합 분석에서 각각 1.0 및 1.2 μM입니다. Cdc42 WT 및 Cdc42Q61L 돌연변이에 대한 EC50은 GDP 결합 분석에서 각각 0.3 및 0.5 μM입니다. 분자 프로브로 사용하십시오. CID44216842 Chemical Structure
  8. GC43306 Compound C108 Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. Compound C108 Chemical Structure
  9. GC91590 DTPD-Q

    2,5-Bis(o-tolylamino)cyclohexa-2,5-diene-1,4-dione,DTPD-quinone

     DTPD-Q is an oxidized derivative of the antioxidant and methylphenyl substituted p-phenylenediamine DTPD. DTPD-Q Chemical Structure
  10. GC14179 Dynole 34-2 Dynole 34-2는 항유사분열 효과가 있는 dynamin GTPase 억제제(dynamin1 및 dynamin2 GTPase 활성에 대해 IC50s=6.9 및 14.2 μM, 각각)입니다. Dynole 34-2는 세포 수포, DNA 단편화 및 PARP 절단에 의해 밝혀진 바와 같이 세포자멸사를 유도합니다. Dynole 34-2는 또한 수용체 매개 세포내이입(RME)을 강력하게 억제합니다. Dynole 34-2 Chemical Structure
  11. GC20107 Fendiline hydrochloride

    Fendiline hydrochloride is a nonselective calcium channel blocker.

     Fendiline hydrochloride Chemical Structure
  12. GC49089 FR900359

    UBO-QIC

     FR900359는 Gαq, Gα11, Gα14와 같은 G 단백질의 저해제로 각각 13.18nM, 10.47nM, 10nM의 IC50 값을 가지고 있고 장식용 식물인 주사근의 잎에서 분리되었다. FR900359 Chemical Structure
  13. GC18260 FTase Inhibitor I

    Farnesyltransferase Inhibitor I

    FTase 억제제 I는 파네실트란스퍼라아제 (FTase; IC50 = 21 nM)의 강력한 억제제로, 게란일게랄리트란스퍼라아제 (GGTase; IC50 = 790 nM)보다 30배 이상 선택적입니다.

     FTase Inhibitor I Chemical Structure
  14. GC52503 FTase Inhibitor II (trifluoroacetate salt)

    Farnesyltransferase Inhibitor II, FTI-II

     A potent, selective inhibitor of farnesyltransferase FTase Inhibitor II (trifluoroacetate salt) Chemical Structure
  15. GC90919 Guanosine 5'-[γ-thio]triphosphate (sodium salt)

    GTP의 가수분해 저항성 아날로그

     Guanosine 5'-[γ-thio]triphosphate (sodium salt) Chemical Structure
  16. GC49033 Guanosine 5’-diphosphate (sodium salt hydrate)

    GDP

     A purine nucleotide Guanosine 5’-diphosphate (sodium salt hydrate) Chemical Structure
  17. GC49703 Guanosine 5’-[γ-thio]triphosphate (lithium salt)

    GTPγS, Guanosine 5'-O-(3-thio)triphosphate, Guanosine 5'-trihydrogen diphosphate monoanhydride Phosphorothioic Acid

     A hydrolysis-resistant analog of GTP Guanosine 5’-[γ-thio]triphosphate (lithium salt) Chemical Structure
  18. GC17852 Gue 1654 Gue 1654는 OXE-R의 변조기입니다. Gue 1654 Chemical Structure
  19. GC15722 HJC 0350 HJC 0350은 IC50이 0.3 µM인 강력하고 특이적인 EPAC2 길항제입니다. HJC 0350 Chemical Structure
  20. GC47477 JKE-1674 JKE-1674는 경구 활성 글루타티온 퍼옥시다제 4(GPX4) 억제제이자 GPX4 억제제 ML-210의 활성 대사 산물입니다. JKE-1674, 니트로이속사졸 고리가 α-니트로케톡심으로 대체된 ML-210의 유사체. JKE-1674는 니트릴 산화물 JKE-1777로 변환할 수 있습니다. JKE-1674는 ML-210과 동일한 방식으로 LOX-IMVI 세포를 죽이고 ferroptosis 억제제에 의해 완전히 구제됩니다. JKE-1674 Chemical Structure
  21. GC47478 JKE-1716 JKE-1716은 강력하고 선택적인 니트로산 함유 GPX4 억제제입니다. JKE-1716 Chemical Structure
  22. GC44020 L-681,217 L-681,217 is an antibiotic originally isolated from S. L-681,217 Chemical Structure
  23. GC47601 Mastoparan (trifluoroacetate salt) A neuropeptide with diverse biological activities Mastoparan (trifluoroacetate salt) Chemical Structure
  24. GC52250 Mevalonate (lithium salt)

    Mevalonic Acid, MVA, Pentanoic Acid

     An intermediate in the mevalonate pathway Mevalonate (lithium salt) Chemical Structure
  25. GC13243 MitMAB

    TTABr, TTAB

     유기 빌딩 블록인 MitMAB은 비대칭 구조의 양이온성 계면활성제입니다. MitMAB Chemical Structure
  26. GC18445 N-Deacetylcolchicine

    NSC 201400

     An inhibitor of microtubule polymerization N-Deacetylcolchicine Chemical Structure
  27. GC11880 OctMAB Dynamin inhibitor OctMAB Chemical Structure
  28. GC44506 Oligomycin D

    26-Demethyloligomycin A

    Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.

     Oligomycin D Chemical Structure
  29. GC44763 PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt)

    DOPI4,5P2, Phosphatidylinositol4,5bisphosphate C8

     The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt) Chemical Structure
  30. GC48094 Spiro-Oxanthromicin A A polyketide Spiro-Oxanthromicin A Chemical Structure
  31. GC91153 Sulfonadyn-47

    다이나믹인 억제제

     Sulfonadyn-47 Chemical Structure

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