Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) |
| Catalog No.GC31783 |
메틸 3,4-다이하이드록시벤조에이트(Protocatechuic acid methyl ester)는 녹차에서 발견되는 항산화 폴리페놀의 주요 대사체입니다. (Protocatechuic acid methyl ester; 메틸 프로토카테츄에이트)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2150-43-8
Sample solution is provided at 25 µL, 10mM.
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Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) alleviates the toxic effects of F- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells[1].
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F- accumulation and oxidative stress. It prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2[2].
[1]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950. [2]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244.
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