>>Signaling Pathways>> Immunology/Inflammation>> Interleukin Related>>NFAT inhibitor, Cell Permeable

NFAT inhibitor, Cell Permeable

Catalog No.GC50243

NFAT 억제제, Cell Permeable은 활성화된 T 세포(NFAT) 억제제의 세포 투과성 핵 인자입니다.

Products are for research use only. Not for human use. We do not sell to patients.

NFAT inhibitor, Cell Permeable Chemical Structure

Cas No.: 592517-80-1

Size 가격 재고 수량
1 mg
US$293.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.

Elloumi et al (2012) A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis. PLoS One 7 e34172 PMID:22479554 |Noguchi et al (2004) A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat.Med. 10 305 PMID:14770176

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