NFAT inhibitor, Cell Permeable |
Catalog No.GC50243 |
NFAT 억제제, Cell Permeable은 활성화된 T 세포(NFAT) 억제제의 세포 투과성 핵 인자입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 592517-80-1
Sample solution is provided at 25 µL, 10mM.
NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.
Elloumi et al (2012) A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis. PLoS One 7 e34172 PMID:22479554 |Noguchi et al (2004) A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat.Med. 10 305 PMID:14770176
Average Rating: 5
(Based on Reviews and 25 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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