Penicillide (Synonyms: Vermixocin A) |
Catalog No.GC40622 |
벼에서 재배된 Talaromyces derxii에서 분리된 Penicillide(Vermixocin A)는 acyl-CoA:cholesterol acyltransferase(ACAT)에 대한 억제 활성을 나타냅니다.
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Cas No.: 55303-92-9
Sample solution is provided at 25 µL, 10mM.
Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 22.9 µM). It is also an antagonist of oxytocin receptors (IC50 = 67 µM). Penicillide inhibits RNA synthesis in P388 murine leukemia cells.
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