>>Signaling Pathways>> Others>> Negative Controls>>Retreversine

Retreversine

Catalog No.GC41468

Retreversine은 Reversine에 대한 비활성 컨트롤입니다. Reversine은 새로운 종류의 ATP-경쟁적 Aurora 키나제 억제제입니다.

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Retreversine Chemical Structure

Cas No.: 1028332-91-3

Size 가격 재고 수량
500μg
US$47.00
재고 있음
1mg
US$91.00
재고 있음
5mg
US$384.00
재고 있음
10mg
US$672.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Terminal differentiation of embryonic progenitor cells to form distinct, adult tissues is the hallmark of organogenesis in complex organisms. However, in mammals including humans, this process is not readily reversible. Reversine is a 2,6-disubstituted purine derivative that was identified using a screening system based on the loss of terminal differentiation markers in C2C12 myoblast cells. Retreversine is an inactive control molecule, created by simply interchanging the 2 and 6-substituents on the purine ring. Retreversine is inactive at 10-fold higher concentrations than reversine in the myoblast assay.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 12 reference(s) in Google Scholar.)

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