Sartorypyrone B |
Catalog No.GC46217 |
Sartorypyrone B는 chevalone C의 2β-acetoxyl 유사체입니다. Sartorypyrone B는 해양 해면 관련 균류 Neosartorya tsunodae(KUFC 9213) 배양물의 에틸 아세테이트 추출물에서 생성됩니다. Sartorypyrone B는 MCF-7, NCI-H460 및 A375-C5에 대해 각각 17.8, 20.5 및 25.0μM의 GI50을 갖는 강력한 성장 억제 활성을 나타냅니다. Sartorypyrone B는 유방 선암종, 비소세포폐암 및 흑색종 질환의 연구에 대한 잠재력이 있습니다.
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Cas No.: 1452396-11-0
Sample solution is provided at 25 µL, 10mM.
Sartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity.1 It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 μM, respectively).
|1. Eamvijarn, A., Gomes, N.M., Dethoup, T., et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron 69(40), 8583-8591 (2013).
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