>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> Drug-Linker Conjugates for ADC>>SPDB-DM4

SPDB-DM4

Catalog No.GC32982

SPDB-DM4는 메이탄신 기반 페이로드(DM4, 튜불린 억제제)를 SPDB 링커를 통해 사용하여 ADC에 대한 약물-링커 접합체로 강력한 항종양 활성을 나타냅니다.

Products are for research use only. Not for human use. We do not sell to patients.

SPDB-DM4 Chemical Structure

Cas No.: 1626359-62-3

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$1,510.00
재고 있음
1mg
US$321.00
재고 있음
5mg
US$873.00
재고 있음

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고객 리뷰

Based on customer reviews.

  • GlpBio Citations

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4) via a SPDB linker, exhibiting potent anti-tumor activity.

[1]. Puja Sapra, et al. Investigational antibody drug conjugates for solid tumors. Journal Expert Opinion on Investigational Drugs Volume 20, 2011-Issue 8.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 18 reference(s) in Google Scholar.)

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