Telithromycin |
Catalog No.GC15110 |
텔리트로마이신(HMR3647)은 구조적으로 마크로라이드와 유사한 새로운 케톨라이드 항생제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 191114-48-4
Sample solution is provided at 25 µL, 10mM.
Telithromycin(HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Target: AntibacterialTelithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. Telithromycin has over 10 times higher affinity to the subunit 50S than erythromycin. In addition, telithromycin strongly bind simultaneously to two domains of 23S RNA of the 50 S ribosomal subunit, where older macrolides bind strongly only to one domain and weakly to the second domain. Telithromycin can also inhibit the formation of ribosomal subunits 50S and 30S. From Wikipedia.
References:
[1]. http://en.wikipedia.org/wiki/Telithromycin
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