Thalidomide 4'-ether-alkylC6-amine |
Catalog No.GC50528 |
탈리도마이드 4'-에테르-알킬C6-아민은 FKBP12F36V 및 BET의 분해제인 PROTAC dTAG-13에 사용되는 합성된 E3 리가제 리간드-링커 접합체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-88-3
Sample solution is provided at 25 µL, 10mM.
Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a C6 alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTACs R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 4 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Nabet et al (2018) The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 14 431 PMID:29581585 |Erb et al (2017) Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 543 270 PMID:28241139
Average Rating: 5
(Based on Reviews and 28 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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