Valnoctamide (Synonyms: NSC 32363, NSC 34092, Valmethamide, Valoctamidum) |
Catalog No.GC41613 |
발프로에이트의 유도체인 발녹타미드(Valmethamide)는 벤조디아제핀-불응성 간질 상태를 억제합니다.
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Cas No.: 4171-13-5
Sample solution is provided at 25 µL, 10mM.
Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
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