Ritanserin (Synonyms: R-55-667) |
Catalog No.GC13883 |
리탄세린(R 55667)은 5-HT2 수용체에 대한 매우 강력하고 상대적으로 선택적이고 경구 활성이며 장기간 작용하는 길항제이며 IC50이 0.9nM이고 히스타민 H1, 도파민 D2, 아드레날린성 α1, 아드레날린성 α2 수용체에 대해 덜 활성입니다 .
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Cas No.: 87051-43-2
Sample solution is provided at 25 µL, 10mM.
Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors[1].
Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC50 of 0.9 nM, less active on Histamine-H1 (IC50, 35 nM), Dopamine-D2 (IC50, 70 nM), Adrenergic-α1 (IC50, 97 nM), Adrenergic-α2 receptor (IC50, 150 nM)[1].
References:
[1]. Leysen JE, et al. Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist. Mol Pharmacol. 1985 Jun;27(6):600-11.
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