>>Signaling Pathways>> JAK/STAT Signaling>> JAK>>Ritlecitinib tosylate

Ritlecitinib tosylate

Catalog No.GC70211

Ritlecitinib tosylate는 33.1 nM의 IC50을 갖는 구강 활성 및 선택적 JAK3억제제이다.

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Ritlecitinib tosylate Chemical Structure

Cas No.: 2192215-81-7

Size 가격 재고 수량
5 mg
US$53.00
재고 있음
10 mg
US$85.00
재고 있음
25 mg
US$169.00
재고 있음
50 mg
US$270.00
재고 있음
100 mg
US$432.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Ritlecitinib tosylate is an orally active and selective JAK3 inhibitor with an IC50 of 33.1 nM. Ritlecitinib tosylate is used for inflammatory and autoimmune diseases research.

References:
[1]. Telliez JB, et al. Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. ACS Chem Biol. 2016 Dec 16;11(12):3442-3451.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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