RMM 46 |
| Catalog No.GC50294 |
RMM 46은 MSK/RSK 계열 키나제에 대한 선택적이고 가역적인 공유 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1307896-46-3
Sample solution is provided at 25 µL, 10mM.
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MSK/RSK family kinase inhibitor. Exhibits selectivity for RSK2 over NEK2 and PLK1 (IC50s are 12, 530 and 2200 nM, respectively). Inhibits MSK1, MSK2, RSK2 and RSK3 in cellular assays. Reduces CREB phosphorylation in HeLa cells.
Miller et al (2013) Electrophilic fragment-based design of reversible covalent kinase inhibitors. J.Am.Chem.Soc. 135 5298 PMID:23540679
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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